Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice.
Scrub typhus is a leading cause of febrile illness in endemic countries due to infection with Orientia tsutsugamushi (Ot), a seriously understudied intracellular bacterium.Pulmonary involvement associated with vascular parasitism in patients is common and can develop into life threatening interstitial pneumonia.The diverse antigenicity of Ot genoty